3-N-BOC-AMINOMETHYL PIPERIDINE-HCl

3-N-BOC-AMINOMETHYL PIPERIDINE-HCl - Names and Identifiers

Name	3-N-Boc-Aminomethylpiperidine.HCL
Synonyms	3-N-Boc-Aminomethylpiperidine.HCL 3-N-BOC-AMINOMETHYL PIPERIDINE-HCl tert-Butyl (piperidin-3-ylMethyl)carbaMate hydrochloride tert-butyl N-(piperidin-3-ylmethyl)carbamate hydrochloride
CAS	1159826-67-1
InChI	InChI=1S/C11H22N2O2.ClH/c1-11(2,3)15-10(14)13-8-9-5-4-6-12-7-9;/h9,12H,4-8H2,1-3H3,(H,13,14);1H

3-N-BOC-AMINOMETHYL PIPERIDINE-HCl - Physico-chemical Properties

Molecular Formula	C11H23ClN2O2
Molar Mass	250.76552
Storage Condition	under inert gas (nitrogen or Argon) at 2-8°C

3-N-BOC-AMINOMETHYL PIPERIDINE-HCl - Introduction

3-Boc-aminomethyl piperidine hydrochloride is a compound with the following properties:
1. appearance: white crystalline powder.
2. solubility: soluble in some organic solvents, such as methanol, ethanol and dichloromethane, and insoluble in water.
3. Stability: relatively stable at room temperature, but avoid exposure to light and air.

In chemical research and drug synthesis, 3-Boc-aminomethylpiperidine hydrochloride has the following uses:
1. as an important intermediate in organic synthesis, involved in the synthesis of a variety of drugs and bioactive compounds.
2. As a protecting group, the nitrogen atom in piperidine can be protected to prevent its reaction from participating in other unnecessary reactions.
3. In drug development, it can be used as a precursor to synthesize various specific drugs.

The method for preparing 3-Boc-aminomethyl piperidine hydrochloride is generally as follows:
Using hydrochloric acid to dissolve aminomethylpiperidine, and then adding 3-tert-butoxycarbene anhydride (Boc-Cl) to react, 3-Boc-aminomethylpiperidine is generated by esterification reaction, and finally 3-Boc-aminomethylpiperidine hydrochloride is generated by hydrochloric acid treatment.

Note the following safety information when using and handling 3-Boc-aminomethyl piperidine hydrochloride:
1. avoid contact with skin and eyes, such as contact should immediately rinse with plenty of water.
2. in the process of operation should maintain good ventilation, avoid inhalation of dust.
3. Do not inhale or swallow, and seek medical assistance immediately if it occurs.
4. Avoid contact with strong oxidants and strong acids to avoid dangerous reactions.

When using 3-Boc-aminomethyl piperidine hydrochloride, relevant laboratory operation specifications should be followed and necessary safety measures should be taken to ensure the smooth progress of the experiment and personal safety.

Last Update：2024-04-09 02:00:41